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Thursday, February 6, 2014

Delayed Presentation of Psoas Abscess following Nephrectomy and Transverse Colon Repair for Penetrating Trauma

We recently saw a patient that presented almost three years after treatment for a gunshot wound to the abdomen with left nephrectomy and primary descending colon repair for a left renal fracture extending to the hilum and a graze wound to the descending colon respectively. Three years following surgery, the patient presented with two weeks of left sided abdominal and flank pain, fevers, and difficulty walking upright secondary to pain. The patient denied any difficulty with diet and denied any urinary complaints. On examination, the patient was febrile with tenderness in the left side of the abdomen, but no rebound.  Labs were significant for a leukocytosis. CT scan showed a multiloculated abscess extending from the left perinephric space. The abscess was percutaneously drained and grew Escherichia coli and viridans streptococcus. The patient’s pain and fever resolved.  He was discharged home.

Delayed presentations of psoas abscesses after nephrectomy are not uncommon, and a review of the literature reveals abscesses presenting three years to twenty-seven years following nephrectomy. Psoas abscesses can be primary or secondary. A primary abscess occurs when the psoas muscle is the focus of infection. A secondary abscess occurs from direct spread from underlying infections generally intestinal in nature. Secondary abscesses can result from Crohn’s disease, ulcerative colitis, appendicitis, diverticulitis, colonic neoplasms, pyelonephritis, and postoperative complications. Common organisms are staphylococcus aureus, Escherichia coli, Proteus mirabilis, Kelbsiella pneumoniae, Pseudomonas aeruginosa, Bacterioides gragilis, and Serratia marcescens.

Patients generally present with fever and flank pain. Computed tomography is the best test to diagnosis a psoas abscess. Treatment is drainage; percutaneous or surgical, followed by culture directed antibiotic therapy.

Risk factors for development of a psoas abscess following nephrectomy include: (1) enteric injury, (2) urinary tract infection which can cause bladder retention and bacteria translocation from the ureteral stump, (3) retained hematoma as culture medium for bacteria growth, immunodeficiency (4), and (5) reaction against foreign bodies including silk suture, fractured tissue, or stone fragments.

References
1.    Di Marco, et al. Psoas abscess ten years after ipsilateral nephrectomy for pyonephrosis. G Chir 2007; 28(4):139-41.
2.    Guillaume MP, Alle JL, Cogan E. Secondary psoas abscess twenty-seven years after nephrectomy. Eur Urol 1994; 25(2):171-3.
3.    Lee et al. Non-tuberculous cold abscess of the psoas muscle-an unusual manifestation of colocutaneous fistula. Arch Orthop Trauma Surg 2000;120:224-5.




Figure legend: Computerized tomography image revealing multiloculated abscess associated with left psoas muscle.

from Dr. Lindsay Petersen

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